Title : Antiallergic effect of KOB03, a polyherbal medicine, on mast cell-mediated allergic responses in ovalbumin-induced allergic rhinitis mouse and human mast cells.

Pub. Date : 2012 Aug 1

PMID : 22687252






1 Functional Relationships(s)
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1 In addition, KOB03 inhibited the production of inflammatory cytokines such as TNF-alpha, IL-1beta, IL-6 and IL-8 in PMA/A23187-stimulated HMC-1 mast cells by suppressing their gene expression and blocking the ERK1/2 and p38 MAPK and NF-kappaB pathways. Calcimycin C-X-C motif chemokine ligand 8 Homo sapiens