Pub. Date : 2012 Sep
PMID : 22683933
7 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effects of palmitic acid on TNF-alpha-induced cytotoxicity in SK-Hep-1 cells. | Palmitic Acid | tumor necrosis factor | Homo sapiens |
| 2 | PA augmented TNF-alpha-induced cytotoxicity, while the unsaturated fatty acids attenuated TNF-alpha-induced cytotoxicity. | Palmitic Acid | tumor necrosis factor | Homo sapiens |
| 3 | In a mechanistic study, PA enhanced TNF-alpha-mediated apoptosis in the absence of oxidative stress, as determined by measuring the cellular glutathione and malondialdehyde levels. | Palmitic Acid | tumor necrosis factor | Homo sapiens |
| 4 | Moreover, PA inhibited the TNF-alpha-induced phosphorylation of AKT, but not c-Jun N-terminal kinase, indicating that inhibition of survival signaling pathways activated by TNF-alpha may explain the effects of PA on TNF-alpha-induced cytotoxicity. | Palmitic Acid | tumor necrosis factor | Homo sapiens |
| 5 | Moreover, PA inhibited the TNF-alpha-induced phosphorylation of AKT, but not c-Jun N-terminal kinase, indicating that inhibition of survival signaling pathways activated by TNF-alpha may explain the effects of PA on TNF-alpha-induced cytotoxicity. | Palmitic Acid | tumor necrosis factor | Homo sapiens |
| 6 | Moreover, PA inhibited the TNF-alpha-induced phosphorylation of AKT, but not c-Jun N-terminal kinase, indicating that inhibition of survival signaling pathways activated by TNF-alpha may explain the effects of PA on TNF-alpha-induced cytotoxicity. | Palmitic Acid | tumor necrosis factor | Homo sapiens |
| 7 | Moreover, PA inhibited the TNF-alpha-induced phosphorylation of AKT, but not c-Jun N-terminal kinase, indicating that inhibition of survival signaling pathways activated by TNF-alpha may explain the effects of PA on TNF-alpha-induced cytotoxicity. | Palmitic Acid | tumor necrosis factor | Homo sapiens |