Title : Donor-specific CD8+ Foxp3+ T cells protect skin allografts and facilitate induction of conventional CD4+ Foxp3+ regulatory T cells.

Pub. Date : 2012 Sep

PMID : 22681667






1 Functional Relationships(s)
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1 In this study, we show that functionally suppressive, alloantigen-specific CD8(+) Foxp3(+) T cells can be induced and significantly expanded by stimulating naive CD8(+) T cells with donor dendritic cells in the presence of IL-2, TGF-beta1 and retinoic acid. Tretinoin forkhead box P3 Homo sapiens