Pub. Date : 2012 Aug
PMID : 22640031
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | Preclinical data showed that the Akt inhibitor, perifosine, sensitized MM cells to lenalidomide and dexamethasone, providing the rationale for this Phase I, multicentre, single-arm study to assess the safety and determine the maximum-tolerated dose (MTD) of perifosine-lenalidomide-dexamethasone in relapsed and relapsed/refractory MM. | Lenalidomide | AKT serine/threonine kinase 1 | Homo sapiens |
2 | Preclinical data showed that the Akt inhibitor, perifosine, sensitized MM cells to lenalidomide and dexamethasone, providing the rationale for this Phase I, multicentre, single-arm study to assess the safety and determine the maximum-tolerated dose (MTD) of perifosine-lenalidomide-dexamethasone in relapsed and relapsed/refractory MM. | Lenalidomide | AKT serine/threonine kinase 1 | Homo sapiens |