Title : Splitomicin inhibits fMLP-induced superoxide anion production in human neutrophils by activate cAMP/PKA signaling inhibition of ERK pathway.

Pub. Date : 2012 Aug 5

PMID : 22634165






1 Functional Relationships(s)
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1 This negative effect was well-correlated with increased cAMP levels via PKA activity and the subsequent inhibition of ERK (p42/p44) phosphorylation to decrease superoxide anion production. Superoxides mitogen-activated protein kinase 1 Homo sapiens