Title : Attenuation of monocrotaline-induced pulmonary arterial hypertension in rats by rosuvastatin.

Pub. Date : 2012 Aug

PMID : 22592772






2 Functional Relationships(s)
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1 At the molecular level, rosuvastatin could inhibit the expression of ROCK-1 (P < 0.05, respectively) and PCNA (P < 0.01, respectively) but restore the expression of eNOS (P < 0.05, respectively). Rosuvastatin Calcium nitric oxide synthase 3 Rattus norvegicus
2 The effects of rosuvastatin seemed to be associated with the regulation of ROCK-1, PCNA, and eNOS expression. Rosuvastatin Calcium nitric oxide synthase 3 Rattus norvegicus