Title : Significant impact of single N-glycan residues on the biological activity of Fc-based antibody-like fragments.

Pub. Date : 2012 Jul 13

PMID : 22589538






1 Functional Relationships(s)
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1 By contrast, glycoforms that lacked core oligosaccharide modifications (i.e., core alpha1,3-fucose and beta1,2-xylose) showed significantly enhanced binding to the Fcgamma receptor IIIa, irrespective of whether plant or human expression systems were used. Oligosaccharides Fc gamma receptor IIIa Homo sapiens