Pub. Date : 2013 Feb
PMID : 22587561
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | The mechanisms of capsaicin-induced OPG expression in HPDL cells were studied using inhibitors. | Capsaicin | TNF receptor superfamily member 11b | Homo sapiens |
| 2 | Treatment with capsaicin induced OPG expression in a dose-dependent manner but did not affect the expression of RANKL. | Capsaicin | TNF receptor superfamily member 11b | Homo sapiens |
| 3 | Capsazepine, the competitive TRPV1 antagonist, significantly abolished the effect of capsaicin on OPG expression in HPDL cells. | Capsaicin | TNF receptor superfamily member 11b | Homo sapiens |
| 4 | Interestingly, capsaicin was able to increase the OPG/RANKL ratio, even in the presence of prostaglandin E2, a potent inducer of RANKL. | Capsaicin | TNF receptor superfamily member 11b | Homo sapiens |