Title : Histamine regulates mucin expression through H1 receptor in airway epithelial cells.

Pub. Date : 2012 Jun

PMID : 22582780






3 Functional Relationships(s)
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1 CONCLUSION: The data suggest that histamine up-regulates MUC2 gene regulation and mucin production in airway epithelial cells through histamine 1 receptor (H1R). Histamine LOC100508689 Homo sapiens
2 Histamine appears to play an important role in the early phase of mucin regulation, which might be effectively blocked by an H1R antagonist. Histamine LOC100508689 Homo sapiens
3 Histamine-induced MUC2 mRNA expression and mucin secretion were significantly suppressed by pretreatment with H1R antagonist. Histamine LOC100508689 Homo sapiens