Title : 7,8,3'-Trihydroxyflavone, a potent small molecule TrkB receptor agonist, protects spiral ganglion neurons from degeneration both in vitro and in vivo.

Pub. Date : 2012 Jun 8

PMID : 22575512






3 Functional Relationships(s)
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1 7,8,3"-Trihydroxyflavone, a potent small molecule TrkB receptor agonist, protects spiral ganglion neurons from degeneration both in vitro and in vivo. 7,8,3'-trihydroxyflavone neurotrophic tyrosine kinase, receptor, type 2 Mus musculus
2 Here we report that 7,8,3"-trihydroxyflavone (7,8,3"-THF), which is a small molecule agonist of tyrosine receptor kinase B (TrkB), promoted SGN survival with high potency both in vitro and in vivo. 7,8,3'-trihydroxyflavone neurotrophic tyrosine kinase, receptor, type 2 Mus musculus
3 Here we report that 7,8,3"-trihydroxyflavone (7,8,3"-THF), which is a small molecule agonist of tyrosine receptor kinase B (TrkB), promoted SGN survival with high potency both in vitro and in vivo. 7,8,3'-trihydroxyflavone neurotrophic tyrosine kinase, receptor, type 2 Mus musculus