Title : The protein kinase C inhibitor, Ro-31-7459, is a potent activator of ERK and JNK MAP kinases in HUVECs and yet inhibits cyclic AMP-stimulated SOCS-3 gene induction through inactivation of the transcription factor c-Jun.

Pub. Date : 2012 Aug

PMID : 22561846






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 We found that cyclic AMP stimulation of HUVECs promoted phosphorylation and activation of JNK MAP kinase and its substrate c-Jun. Cyclic AMP mitogen-activated protein kinase 8 Homo sapiens