Title : Bifunctional thrombin inhibitors based on the sequence of hirudin45-65.

Pub. Date : 1990 Dec 15

PMID : 2254323






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 N alpha-Acetyl[D-Phe45, Arg47] hirudin45-65 (P53) emerged as a pure competitive inhibitor with a Ki = 2.8 +/- 0.9 nM and IC50 = 4.0 +/- 0.8 nM (human alpha-thrombin) and is designated as a "bifunctional" inhibitor. Cysteine tumor protein p53 Homo sapiens