Title : Synthesis, spectroscopic characterization, photochemical and photophysical properties and biological activities of ruthenium complexes with mono- and bi-dentate histamine ligand.

Pub. Date : 2012 Jun 14

PMID : 22539182






1 Functional Relationships(s)
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1 Pharmacological studies showed that the complexes present a moderate inhibition of AChE with an IC(50) of 21 mumol L(-1) (referred to risvagtini, IC(50) 181 mumol L(-1) and galantamine IC(50) 0.006 mumol L(-1)) with no appreciable cytotoxicity toward to the HeLa cells (50% cell viability at 925 mumol L(-1)). Galantamine acetylcholinesterase (Cartwright blood group) Homo sapiens