Pub. Date : 1990
PMID : 2253658
6 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Effect of furosemide on angiotensin II-mediated prostaglandin I2 production in hypertensive subjects. | Furosemide | angiotensinogen | Homo sapiens |
| 2 | The role of angiotensin II (AII) in Prostaglandin I2 (PGI2) production following furosemide has been examined in a placebo-controlled, cross-over study. | Furosemide | angiotensinogen | Homo sapiens |
| 3 | The role of angiotensin II (AII) in Prostaglandin I2 (PGI2) production following furosemide has been examined in a placebo-controlled, cross-over study. | Furosemide | angiotensinogen | Homo sapiens |
| 4 | Urinary excretion of 6-keto-PGF1 alpha (a metabolite of PGI2) and PGE2, PRA and AII was increased following furosemide without captopril pretreatment. | Furosemide | angiotensinogen | Homo sapiens |
| 5 | The rises in urinary 6-keto-PGF1 alpha and PGE2, and plasma AII after furosemide were prevented by the captopril pretreatment. | Furosemide | angiotensinogen | Homo sapiens |
| 6 | The data indicate that the effect of furosemide on PGI2 production, as reflected by the urinary excretion of 6-keto-PGF1 alpha, was mediated by an action of AII. | Furosemide | angiotensinogen | Homo sapiens |