Title : Differential effects of an O-GlcNAcase inhibitor on tau phosphorylation.

Pub. Date : 2012

PMID : 22536363






1 Functional Relationships(s)
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1 These results suggest that acute high-dose thiamet-G injection can not only directly antagonize tau phosphorylation, but also stimulate GSK-3beta activity, with the downstream consequence being site-specific, bi-directional regulation of tau phosphorylation in the mammalian brain. thiamet glycogen synthase kinase 3 beta Homo sapiens