Pub. Date : 2012 May 11
PMID : 22525672
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | F9 embryonic carcinoma (EC) cells undergo extra-embryonic endodermal (ExE) differentiation in response to retinoic acid (RA) treatment, which induces the expression of two isoforms (p96 and p67) of the adaptor protein, Disabled-2 (Dab2). | Tretinoin | DAB adaptor protein 2 | Homo sapiens |
2 | F9 embryonic carcinoma (EC) cells undergo extra-embryonic endodermal (ExE) differentiation in response to retinoic acid (RA) treatment, which induces the expression of two isoforms (p96 and p67) of the adaptor protein, Disabled-2 (Dab2). | Tretinoin | DAB adaptor protein 2 | Homo sapiens |
3 | F9 embryonic carcinoma (EC) cells undergo extra-embryonic endodermal (ExE) differentiation in response to retinoic acid (RA) treatment, which induces the expression of two isoforms (p96 and p67) of the adaptor protein, Disabled-2 (Dab2). | Tretinoin | DAB adaptor protein 2 | Homo sapiens |
4 | F9 embryonic carcinoma (EC) cells undergo extra-embryonic endodermal (ExE) differentiation in response to retinoic acid (RA) treatment, which induces the expression of two isoforms (p96 and p67) of the adaptor protein, Disabled-2 (Dab2). | Tretinoin | DAB adaptor protein 2 | Homo sapiens |
5 | During the RA-induced differentiation process, Dab2 expression is induced by the GATA factors in a coherent feed-forward loop; on the other hand, we showed that p96 regulates GATA-4 in a positive feed-back manner in this study. | Tretinoin | DAB adaptor protein 2 | Homo sapiens |