Title : Nicotine stimulates proliferation and inhibits apoptosis in colon cancer cell lines through activation of survival pathways.

Pub. Date : 2012 Nov

PMID : 22520577






2 Functional Relationships(s)
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1 Nicotine induced a statistically significant increase in the expression of PI3K and in P-Akt/Akt ratio as well as in the expression of PKC, ERK1/2, survivin, and P-Bcl2 (Ser70) in both cell lines. Nicotine AKT serine/threonine kinase 1 Homo sapiens
2 Nicotine induced a statistically significant increase in the expression of PI3K and in P-Akt/Akt ratio as well as in the expression of PKC, ERK1/2, survivin, and P-Bcl2 (Ser70) in both cell lines. Nicotine AKT serine/threonine kinase 1 Homo sapiens