Title : XIAP inhibition and generation of reactive oxygen species enhances TRAIL sensitivity in inflammatory breast cancer cells.

Pub. Date : 2012 Jul

PMID : 22508521






1 Functional Relationships(s)
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1 Embelin treatment resulted in activation of extracellular signal-regulated kinase (ERK)1/2 and ROS accumulation, which correlated with downregulation of antioxidant protein SOD1 and consumption of redox modulator reduced glutathione in the XIAP-overexpressing cells. Glutathione mitogen-activated protein kinase 1 Homo sapiens