Pub. Date : 2012 Aug
PMID : 22504573
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Meta-analysis of the effect of MDR1 C3435 polymorphism on tacrolimus pharmacokinetics in renal transplant recipients. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 2 | BACKGROUND: The published data revealed conflicting results of the polymorphism of MDR1 exon 26 SNP C3435T on the pharmacokinetics of tacrolimus in different post transplant times; thus, the aim was to perform a meta-analysis of different post transplant times to investigate the influence of SNP C3435T on the tacrolimus pharmacokinetics. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |
| 3 | CONCLUSIONS: Our meta-analysis of available studies has demonstrated a definite correlation between the SNP C3435T in MDR1 gene and pharmacokinetics of tacrolimus. | Tacrolimus | ATP binding cassette subfamily B member 1 | Homo sapiens |