Title : Organophosphate-induced brain damage: mechanisms, neuropsychiatric and neurological consequences, and potential therapeutic strategies.

Pub. Date : 2012 Jun

PMID : 22498093






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1 Organophosphate (OP)-induced brain damage is defined as progressive damage to the brain, resulting from the cholinergic neuronal excitotoxicity and dysfunction induced by OP-induced irreversible AChE inhibition. Organophosphates acetylcholinesterase (Cartwright blood group) Homo sapiens