Title : Pathophysiology of renal calcium handling in acromegaly: what lies behind hypercalciuria?

Pub. Date : 2012 Jun

PMID : 22496496






1 Functional Relationships(s)
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1 CONCLUSION: The IGF-I-mediated and PTH-independent increase in calcitriol synthesis in acromegaly is responsible for both absorptive hypercalciuria and increased fasting plasma calcium linked to enhanced distal tubular calcium reabsorption, as shown by the selectively diminished calciuric response to furosemide. Furosemide insulin like growth factor 1 Homo sapiens