Title : Differential estrogenic actions of endocrine-disrupting chemicals bisphenol A, bisphenol AF, and zearalenone through estrogen receptor α and β in vitro.

Pub. Date : 2012 Jul

PMID : 22494775






2 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 ERE-mediated activation by BPA and BPAF was via the AF-2 function of ERalpha, but Zea activated via both the AF-1 and AF-2 functions. 4,4'-hexafluorisopropylidene diphenol estrogen receptor 1 Homo sapiens
2 CONCLUSION: BPA and BPAF can function as EDCs by acting as cell type-specific agonists (>= 10 nM) or antagonists (<= 10 nM) for ERalpha and ERbeta. 4,4'-hexafluorisopropylidene diphenol estrogen receptor 1 Homo sapiens