Pub. Date : 2012 Jul 6
PMID : 22493436
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Nigericin-induced impairment of autophagic flux in neuronal cells is inhibited by overexpression of Bak. | Nigericin | BCL2-antagonist/killer 1 | Mus musculus |
| 2 | To investigate whether and how Bak exerts a regulatory role on autophagy-related events, we treated independent cell lines, including MN9D neuronal cells, with nigericin, a K(+)/H(+) ionophore. | Nigericin | BCL2-antagonist/killer 1 | Mus musculus |
| 3 | Subsequent biochemical and electron microscopic studies revealed that overexpressed Bak maintained autophagic flux and reduced the area occupied by swollen vacuoles in nigericin-treated cells. | Nigericin | BCL2-antagonist/killer 1 | Mus musculus |