Pub. Date : 2012 Apr
PMID : 22493349
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | 5-aminosalicylic acid mediates expression of cyclooxygenase-2 and 15-hydroxyprostaglandin dehydrogenase to suppress colorectal tumorigenesis. | Mesalamine | hydroxyprostaglandin dehydrogenase 15 (NAD) | Mus musculus |
| 2 | Here we determined the effect of 5-aminosalicylic acid (5-ASA) on COX-2 and 15-PGDH expression and investigated its preventive effect for colorectal cancer (CRC). | Mesalamine | hydroxyprostaglandin dehydrogenase 15 (NAD) | Mus musculus |
| 3 | Here we determined the effect of 5-aminosalicylic acid (5-ASA) on COX-2 and 15-PGDH expression and investigated its preventive effect for colorectal cancer (CRC). | Mesalamine | hydroxyprostaglandin dehydrogenase 15 (NAD) | Mus musculus |
| 4 | CONCLUSION: 5-ASA exerts a preventive effect against colorectal tumor development through mediation of COX-2 and 15-PGDH expression. | Mesalamine | hydroxyprostaglandin dehydrogenase 15 (NAD) | Mus musculus |