Title : Resveratrol inhibits paraquat-induced oxidative stress and fibrogenic response by activating the nuclear factor erythroid 2-related factor 2 pathway.

Pub. Date : 2012 Jul

PMID : 22493042






1 Functional Relationships(s)
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1 PQ at 10 muM stimulated production of inflammatory and profibrogenic factors (tumor necrosis factor alpha, interleukin 6, and transforming growth factor beta1) and induced the transformation of normal human lung fibroblasts (WI38-VA13) to myofibroblasts; both effects were inhibited by Res. Paraquat tumor necrosis factor Homo sapiens