Pub. Date : 2012 Jul
PMID : 22490780
2 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | PGE2 is a well-established endogenous pyrogen activated by proinflammatory cytokine interleukin (IL)-1beta. | Dinoprostone | interleukin 1 beta | Mus musculus |
| 2 | Here we show that P2X7R activation is required for the release of PGE2 and other autacoids independent of inflammasome activation, with an ATP EC(50) for PGE2 and IL-1beta release of 1.58 and 1.23 mM, respectively. | Dinoprostone | interleukin 1 beta | Mus musculus |