Title : Time-dependent inhibition and estimation of CYP3A clinical pharmacokinetic drug-drug interactions using plated human cell systems.

Pub. Date : 2012 Jul

PMID : 22490230






1 Functional Relationships(s)
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1 The apparent K(I) estimates derived from the various systems displayed a range of variability from 3-fold for clarithromycin (5.4-17.7 muM) to 6-fold for verapamil (1.9-12.6 muM). Clarithromycin latexin Homo sapiens