Title : Is there sufficient evidence to consider the use of 11β-hydroxysteroid dehydrogenase type 1 inhibition in children?

Pub. Date : 2012 Aug

PMID : 22486586






1 Functional Relationships(s)
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1 Based on current literature, the concept of inhibition of 11beta-HSD1 is considered a potentially effective mean to regulate local cortisol levels in the paediatric population, and 11beta-HSD1 inhibitors may provide a valuable target and treatment option for the metabolic syndrome in paediatric patients. Hydrocortisone hydroxysteroid 11-beta dehydrogenase 1 Homo sapiens