Pub. Date : 2012 Apr
PMID : 22476196
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We found that amyloid-beta peptide (Abeta) oligomers, synaptotoxins that accumulate in the brains of AD patients, activated the JNK/TNF-alpha pathway, induced IRS-1 phosphorylation at multiple serine residues, and inhibited physiological IRS-1pTyr in mature cultured hippocampal neurons. | Serine | mitogen-activated protein kinase 8 | Homo sapiens |