Title : Interaction of cisplatin with human superoxide dismutase.

Pub. Date : 2012 Apr 25

PMID : 22471402






1 Functional Relationships(s)
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Compound Name
Protein Name
Organism
1 cis-Diamminedichloroplatinum(II) (cisplatin) is able to interact with human superoxide dismutase (hSOD1) in the disulfide oxidized apo form with a dissociation constant of 37 +- 3 muM through binding cysteine 111 (Cys111) located at the edge of the subunit interface. Cysteine superoxide dismutase 1 Homo sapiens