Title : Molecular cloning of the human XRCC1 gene, which corrects defective DNA strand break repair and sister chromatid exchange.

Pub. Date : 1990 Dec

PMID : 2247054






1 Functional Relationships(s)
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Protein Name
Organism
1 The CHO mutant EM9 has 10-fold-higher sensitivity to ethyl methanesulfonate, 1.8-fold-higher sensitivity to ionizing radiation, a reduced capacity to rejoin single-strand DNA breaks, and a 10-fold-elevated level of sister chromatid exchange compared with the CHO parental cells. Ethyl Methanesulfonate ERCC excision repair 2, TFIIH core complex helicase subunit Homo sapiens