Title : A gene nanocomplex conjugated with monoclonal antibodies for targeted therapy of hepatocellular carcinoma.

Pub. Date : 2012 Jun

PMID : 22469295






2 Functional Relationships(s)
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Compound Name
Protein Name
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1 The biodegradable cationic polyethylenimine-grafted-alpha,beta-poly(N-3-hydroxypropyl)-DL-aspartamide (PHPA-PEI) was used for complexing pDNA to form the PHPA-PEI/pDNA nanoparticle, and then 9B9 mAb, an anti-epidermal growth factor receptor (anti-EGFR) monoclonal antibody, was conjugated to produce the PHPA-PEI/pDNA/9B9 mAb (PP9mN) complex. Polyethyleneimine epidermal growth factor receptor Homo sapiens
2 The biodegradable cationic polyethylenimine-grafted-alpha,beta-poly(N-3-hydroxypropyl)-DL-aspartamide (PHPA-PEI) was used for complexing pDNA to form the PHPA-PEI/pDNA nanoparticle, and then 9B9 mAb, an anti-epidermal growth factor receptor (anti-EGFR) monoclonal antibody, was conjugated to produce the PHPA-PEI/pDNA/9B9 mAb (PP9mN) complex. Polyethyleneimine epidermal growth factor receptor Homo sapiens