Title : Elusive proximal signals of beta-cells for insulin secretion.

Pub. Date : 1990 Dec

PMID : 2245873






1 Functional Relationships(s)
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1 Because glyceraldehyde, which enters metabolism at the triose phosphates in the glycolytic pathway, is a potent insulin secretagogue but pyruvate, which is metabolized in the mitochondrion, is not an insulin secretagogue, the proximal signal for glucose-induced insulin release originates with an interaction between the central part of the glycolytic pathway and mitochondrial metabolism. Phosphates insulin Homo sapiens