Title : Serum levels of soluble secreted α-Klotho are decreased in the early stages of chronic kidney disease, making it a probable novel biomarker for early diagnosis.

Pub. Date : 2012 Oct

PMID : 22457086






2 Functional Relationships(s)
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1 Serum levels of soluble alpha-Klotho in chronic kidney disease (CKD) patients have not previously been determined, especially in relation with FGF23 and creatinine levels. Creatinine klotho Homo sapiens
2 RESULTS: Serum soluble alpha-Klotho levels were associated positively with estimated glomerular filtration rate (eGFR) (P < 0.0001) and inversely with serum creatinine level (P < 0.01). Creatinine klotho Homo sapiens