Title : Chemerin inhibits IGF-1-induced progesterone and estradiol secretion in human granulosa cells.

Pub. Date : 2012 Jun

PMID : 22447628






2 Functional Relationships(s)
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1 rhChem (10 or 100 ng/ml) significantly decreased insulin-like growth factor-1 (IGF-1) (10(-8) M)-induced secretion of progesterone and estradiol (as determined by radioimmunoassay) but did not affect basal-or FSH (10(-8) M)-induced steroid secretion in hGCs and KGN cells. Steroids insulin like growth factor 1 Homo sapiens
2 rhChem (10 or 100 ng/ml) significantly decreased insulin-like growth factor-1 (IGF-1) (10(-8) M)-induced secretion of progesterone and estradiol (as determined by radioimmunoassay) but did not affect basal-or FSH (10(-8) M)-induced steroid secretion in hGCs and KGN cells. Steroids insulin like growth factor 1 Homo sapiens