Title : Differential effects of cocaine access and withdrawal on glutamate type 1 transporter expression in rat nucleus accumbens core and shell.

Pub. Date : 2012 May 17

PMID : 22433294






4 Functional Relationships(s)
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1 Differential effects of cocaine access and withdrawal on glutamate type 1 transporter expression in rat nucleus accumbens core and shell. Cocaine solute carrier family 1 member 2 Rattus norvegicus
2 Consistent with this view, glutamate type 1 transporter (GLT1), the transporter responsible for >90% of glutamate uptake, is downregulated in NAc after several days of withdrawal in rats previously trained to self-administer cocaine under limited access conditions (1-2 h/d). Cocaine solute carrier family 1 member 2 Rattus norvegicus
3 Consistent with this view, glutamate type 1 transporter (GLT1), the transporter responsible for >90% of glutamate uptake, is downregulated in NAc after several days of withdrawal in rats previously trained to self-administer cocaine under limited access conditions (1-2 h/d). Cocaine solute carrier family 1 member 2 Rattus norvegicus
4 Here, we determined the combined effects of manipulating cocaine access and withdrawal on GLT1 expression in NAc core and shell. Cocaine solute carrier family 1 member 2 Rattus norvegicus