Title : Chemopreventive effects of RXR-selective rexinoid bexarotene on intestinal neoplasia of Apc(Min/+) mice.

Pub. Date : 2012 Feb

PMID : 22431924






1 Functional Relationships(s)
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1 Intestinal tumors of bexarotene-fed mice showed significantly reduced expression of proliferating cell nuclear antigen (60%, P < .0001), cyclin D1, and cyclooxygenase 2 and increased RXR-alpha messenger RNA and uptake of oleate (34%, P < .01). Bexarotene cyclin D1 Mus musculus