Title : Inhibitory effects of lycopene on HMGB1-mediated pro-inflammatory responses in both cellular and animal models.

Pub. Date : 2012 Jun

PMID : 22429818






2 Functional Relationships(s)
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1 Lycopene inhibited lipopolysaccharide (LPS)-mediated release of HMGB1, expression of HMGB1-mediated tumor necrosis factor (TNF)-secretory phospholipase A2 (sPLA2)-IIA, and HMGB1-mediated pro-inflammatory signaling responses in endothelial cells. Lycopene tumor necrosis factor Homo sapiens
2 Lycopene inhibited lipopolysaccharide (LPS)-mediated release of HMGB1, expression of HMGB1-mediated tumor necrosis factor (TNF)-secretory phospholipase A2 (sPLA2)-IIA, and HMGB1-mediated pro-inflammatory signaling responses in endothelial cells. Lycopene tumor necrosis factor Homo sapiens