Title : Methyl parathion acute toxicity: prophylaxis and therapy with memantine and atropine.

Pub. Date : 1990 May-Jun

PMID : 2241428






2 Functional Relationships(s)
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1 These results suggest that memantine may counteract the acute methyl parathion toxicity by (a) protection of acetylcholinesterase from inhibition, (b) rapid reactivation of inhibited acetylcholinesterase and (c) rapid bioelimination of methyl parathion, in addition to cholinolytic effects of atropine sulfate. Memantine acetylcholinesterase Rattus norvegicus
2 These results suggest that memantine may counteract the acute methyl parathion toxicity by (a) protection of acetylcholinesterase from inhibition, (b) rapid reactivation of inhibited acetylcholinesterase and (c) rapid bioelimination of methyl parathion, in addition to cholinolytic effects of atropine sulfate. Memantine acetylcholinesterase Rattus norvegicus