Pub. Date : 2012 Oct
PMID : 22407903
3 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Th2 cytokine-mediated methimazole-induced acute liver injury in mice. | Methimazole | heart and neural crest derivatives expressed 2 | Mus musculus |
| 2 | The hepatic expression of mRNA for Th2 cell-related factors, such as GATA-binding protein, macrophage inflammatory protein-2 (MIP-2) and plasma IL-4 levels, as well as plasma AST and ALT levels, was significantly increased in mice treated with MTZ. | Methimazole | heart and neural crest derivatives expressed 2 | Mus musculus |
| 3 | In conclusion, this report is the first to demonstrate that Th2 cytokine-mediated immune responses are involved in MTZ-induced acute liver injury in mice. | Methimazole | heart and neural crest derivatives expressed 2 | Mus musculus |