Title : The protein phosphatase PP2A/Bα binds to the microtubule-associated proteins Tau and MAP2 at a motif also recognized by the kinase Fyn: implications for tauopathies.

Pub. Date : 2012 Apr 27

PMID : 22403409






1 Functional Relationships(s)
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1 Remarkably, the protein-tyrosine kinase Fyn, which binds to the proline-rich RTPPKSP motif conserved in both MAP2 and tau, inhibits the interaction of PP2A/Balpha with either tau or MAP2c. Proline FYN proto-oncogene, Src family tyrosine kinase Homo sapiens