Title : Molecular alterations of isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes and additional genetic mutations in newly diagnosed acute myeloid leukemia patients.

Pub. Date : 2012 Mar 7

PMID : 22397365






1 Functional Relationships(s)
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1 BACKGROUND: Isocitrate dehydrogenase 1 and 2 (IDH1 and IDH2) metabolic genes encode cytosolic and mitochondrial enzymes that catalyze the conversion of isocitrate to alpha-ketoglutarate. isocitric acid isocitrate dehydrogenase (NADP(+)) 2 Homo sapiens