Title : Lipopolysaccharide activates ERK-PARP-1-RelA pathway and promotes nuclear factor-κB transcription in murine macrophages.

Pub. Date : 2012 May

PMID : 22391342






1 Functional Relationships(s)
Download
Sentence
Compound Name
Protein Name
Organism
1 ERK inhibitor blocked the interaction of PARP-1 with ERK1/2, phosphorylation of PARP-1, and poly(ADP-ribosyl)ation of p65, suggesting that ERK-dependent phosphorylation of PARP-1 regulates PARP-1 activity and NF-kappaB activation. poly(adp-ribosyl) poly (ADP-ribose) polymerase family, member 1 Mus musculus