Title : Nicotinic acetylcholine receptor α7 and β4 subunits contribute nicotine-induced apoptosis in periodontal ligament stem cells.

Pub. Date : 2012 Apr

PMID : 22382680






2 Functional Relationships(s)
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1 Western blot analysis confirmed that p53 proteins were phosphorylated by nicotine. Nicotine tumor protein p53 Homo sapiens
2 Under various doses of nicotine, a decrease in the anti-apoptotic protein Bcl-2, but an increase in p53 and cleaved caspase-3 protein levels, was detected in a dose-dependent manner. Nicotine tumor protein p53 Homo sapiens