Pub. Date : 2012
PMID : 22382327
4 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | Cytochrome P450 2A6 (CYP2A6) catalyzes important metabolic reactions of many xenobiotic compounds, including coumarin, nicotine, cotinine, and clinical drugs. | coumarin | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
| 2 | Cytochrome P450 2A6 (CYP2A6) catalyzes important metabolic reactions of many xenobiotic compounds, including coumarin, nicotine, cotinine, and clinical drugs. | coumarin | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
| 3 | In the case of coumarin 7-hydroxylation, CYP2A6*8 and *35 displayed increased K(m) values whereas CYP2A6*18 and *19 showed decreased k(cat) values, which resulted in lower catalytic efficiencies (k(cat)/K(m)). | coumarin | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |
| 4 | In the case of coumarin 7-hydroxylation, CYP2A6*8 and *35 displayed increased K(m) values whereas CYP2A6*18 and *19 showed decreased k(cat) values, which resulted in lower catalytic efficiencies (k(cat)/K(m)). | coumarin | cytochrome P450 family 2 subfamily A member 6 | Homo sapiens |