Pub. Date : 2012 Apr
PMID : 22365563
1 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
| 1 | We have demonstrated that quinazolin-4(3H)-one, a nicotinamide (NI) mimic with PARP-1 inhibitory activity in the high micromolar range (IC(50) = 5.75 muM) could be transformed into highly active derivatives with only marginal increase in molecular weight. | Niacinamide | poly(ADP-ribose) polymerase 1 | Homo sapiens |