Title : Functional consequence of positive selection revealed through rational mutagenesis of human myeloperoxidase.

Pub. Date : 2012 Aug

PMID : 22355012






1 Functional Relationships(s)
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Protein Name
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1 Whereas all MHPs oxidize specific halides to generate the corresponding hypohalous acid, MPO is unique in its capacity to oxidize chloride at physiologic pH to produce hypochlorous acid (HOCl), a potent microbicide that contributes to neutrophil-mediated host defense against infection. Chlorides myeloperoxidase Homo sapiens