Pub. Date : 2012 May
PMID : 22348616
5 Functional Relationships(s)Download |
Sentence | Compound Name | Protein Name | Organism |
1 | In contrast, the ASAD individuals with the "normal pregnenolone production" genotype expressed low TSPO levels. | Pregnenolone | translocator protein | Homo sapiens |
2 | RESULTS: The genotype with the lowest TSPO expression levels was the "normal pregnenolone production" genotype in the ASAD group. | Pregnenolone | translocator protein | Homo sapiens |
3 | CONCLUSIONS: ASAD individuals who expressed normal TSPO levels exhibited the "reduced pregnenolone production" genotype. | Pregnenolone | translocator protein | Homo sapiens |
4 | It is possible that low TSPO expression levels could compromise normal pregnenolone production. | Pregnenolone | translocator protein | Homo sapiens |
5 | Such evidence may have therapeutic implications because it has been documented that drugs targeting TSPO increased pregnenolone production and have anxiolytic effects. | Pregnenolone | translocator protein | Homo sapiens |