Title : P2X7 receptor-NADPH oxidase axis mediates protein radical formation and Kupffer cell activation in carbon tetrachloride-mediated steatohepatitis in obese mice.

Pub. Date : 2012 May 1

PMID : 22343416






1 Functional Relationships(s)
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1 The free radical-mediated oxidation of cellular macromolecules, which was NADPH oxidase and P2X7 receptor-dependent, correlated well with the release of TNF-alpha and MCP-2 from Kupffer cells. Free Radicals tumor necrosis factor Mus musculus