Title : A phorbol ester-regulated ribonuclease system controlling transforming growth factor beta 1 gene expression in hematopoietic cells.

Pub. Date : 1990 Nov

PMID : 2233728






5 Functional Relationships(s)
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1 12-Tetradecanoylphorbol-13-acetate (TPA)-induced differentiation of U937 promonocytes leads to a 30-fold increase in transforming growth factor beta 1 (TGF-beta 1) gene expression, and this effect results from a stabilized mRNA. Tetradecanoylphorbol Acetate transforming growth factor beta 1 Homo sapiens
2 12-Tetradecanoylphorbol-13-acetate (TPA)-induced differentiation of U937 promonocytes leads to a 30-fold increase in transforming growth factor beta 1 (TGF-beta 1) gene expression, and this effect results from a stabilized mRNA. Tetradecanoylphorbol Acetate transforming growth factor beta 1 Homo sapiens
3 12-Tetradecanoylphorbol-13-acetate (TPA)-induced differentiation of U937 promonocytes leads to a 30-fold increase in transforming growth factor beta 1 (TGF-beta 1) gene expression, and this effect results from a stabilized mRNA. Tetradecanoylphorbol Acetate transforming growth factor beta 1 Homo sapiens
4 12-Tetradecanoylphorbol-13-acetate (TPA)-induced differentiation of U937 promonocytes leads to a 30-fold increase in transforming growth factor beta 1 (TGF-beta 1) gene expression, and this effect results from a stabilized mRNA. Tetradecanoylphorbol Acetate transforming growth factor beta 1 Homo sapiens
5 Related studies in vitro showed that postnuclear extracts of U937 promonocytes contain a ribonuclease system that degrades TGF-beta 1 mRNA selectively and that this system is completely blocked by prior treatment of the cells with TPA. Tetradecanoylphorbol Acetate transforming growth factor beta 1 Homo sapiens